Management of Anthracycline Extravasation Injuries
نویسندگان
چکیده
منابع مشابه
Anthracycline extravasation injuries: management with dexrazoxane
The application of anthracyclines in anticancer therapy may result in accidental extravasation injury and can be a serious complication of their use. Tissue necrosis with skin ulceration is a possible outcome in the inadvertent extravasation of anthracyclines during intravenous administration. Until recently, there has been no effective treatment against the devastating effect of extravasated a...
متن کاملTCRM-3694-anthracycline extravasation
Correspondence: Karin Jordan Clinic for internal Medicine iv, Department for Oncology and Haematology, University Hospital Halle, ernst-Grube-Str. 40, 06120 Halle (Saale), Germany Tel +49 (0) 345/557-2924 Fax +49 (0) 345/557-2950 email [email protected] Abstract: The application of anthracyclines in anticancer therapy may result in accidental extravasation injury and can be a se...
متن کاملManagement of anthracycline extravasation into the pleural space
Anthracycline extravasation is a feared complication of intravenous (i.v.) chemotherapy due to the tissue toxicity of this group of drugs. We describe a 54-year-old woman with history of stage IIIa breast cancer, receiving adjuvant chemotherapy consisting of doxorubicin and cyclophosphamide. The chemotherapy was administered through a Poweport® device, the position of which was confirmed with f...
متن کاملExtravasation injuries.
OBJECTIVES To evaluate the time and type of treatment following extravasation from intravenous infusion and the sequelae of the injuries. METHOD The charts of 12 patients who were referred to the Plastic and Orthopaedic Services at the University Hospital of the West Indies were reviewed. The study period was between May 2003 and January 2007. Data were collected on age, gender, site of extra...
متن کاملTreatment of anthracycline extravasation with dexrazoxane.
Accidental extravasation of anthracyclines is a feared complication. Present treatment consists of local cooling and extensive surgical debridement, which often results in severe morbidity. All clinically important anthracyclines are topoisomerase II poisons that are antagonized by topoisomerase II catalytic inhibitors such as dexrazoxane. Therefore, we investigated whether dexrazoxane protects...
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ژورنال
عنوان ژورنال: Annals of Pharmacotherapy
سال: 2007
ISSN: 1060-0280,1542-6270
DOI: 10.1345/aph.1h700